Perpignan lost 22-11 to Bordeaux-Begles on Sunday in a record 11th straight league defeat in one season for a Top 14 club.
The Catalans take over from Mont de Marsan who failed to win on 10 occasions in the top-flight in 2012-13.
Bordeaux-Begles move up to sixth in the table with their second victory in a row and remain unbeaten under interim coach, former England back-rower Joe Worsley.
Winger Romain Buros scored twice and France scrum-half Baptiste Serin dotted down for the visitors at Stade Aime Giral.
Captain Karl Chateau crossed before Enzo Selponi kicked two penalty goals in a dismal display by Perpignan, whose coach Christian Lanta and his assistants were awarded contract extensions last week.
Later, second-placed Toulouse welcome Stade Francais looking to close the gap on leaders Clermont who claimed a hard-fought 28-23 win at Montpellier on Saturday, moving eight points clear at the top of the league.
Elsewhere, champions Castres were stunned 16-13 at home by lowly Agen, Lyon thumped Pau 30-10, La Rochelle won their fifth straight game as they edged Racing 92 16-11 in incessant rain and Toulon rose to 10th place beating fellow strugglers Grenoble 22-3.
© Agence France-Presse (additional edits from Chris Kelleher)