It looked as though Tottenham Hotspur were about to put some poor league results behind them with a win at the San Siro.
Minus the quartet of Hugo Lloris, Toby Alderweireld, Kieran Trippier and Dele Alli, Spurs nonetheless were impressive in their Champions League opener against Inter Milan.
Their first half was quiet with Harry Kane largely an isolated figure, but Christian Eriksen, who was their most influential player in that period, scored in the 53rd minute to put the away side ahead.
The rebound from his initial shot took a big deflection off Joao Miranda to do just enough to wrong-foot keeper Samir Handanovic.
The likes of Eric Lamela and Heung Min Son threatened to double their lead, but they were ultimately made to pay, first by an absolute stunner from Mauro Icardi, who had been largely anonymous up until then.
His volley in the 85th minute was the catalyst for an almighty barrage aimed at Michel Vorm for the remainder of the game.
In added time, Icardi almost scored a header. From the resulting corner, there was a prolonged scramble in the box, but it was the next set piece that would seal Spurs’ fate.
Stefan de Vrij headed the ball towards goal, with Martias Vecino getting on the receiving end before anyone else could.
This marks Tottenham’s third straight 2-1 defeat, suffered against Watford, Liverpool and now Inter Milan.